| 发明名称 |
Regulated apoptosis |
| 摘要 |
We have developed a general procedure for the regulated (inducible) dimerization or oligomerization of intracellular proteins and disclose methods and materials for using that procedure to regulatably initiate cell-specific apoptosis (programmed cell death) in genetically engineered cells.
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| 申请公布号 |
US6316418(B1) |
申请公布日期 |
2001.11.13 |
| 申请号 |
US19990302629 |
申请日期 |
1999.04.30 |
| 申请人 |
BOARD OF TRUSTEES OF LELAND STANFORD JUNIOR UNIVERSITY;PRESIDENT AND FELLOWS OF HARVARD COLLEGE |
发明人 |
CRABTREE GERALD;SCHREIBER STUART;SPENCER DAVID;WANDLESS THOMAS;BELSHAW PETER;HO STEFFAN N |
| 分类号 |
A61K38/00;A61K47/48;A61K48/00;A61P43/00;C07D498/18;C07F5/02;C07H19/01;C07K7/64;C07K14/395;C07K14/705;C07K14/71;C07K14/715;C07K14/725;C12N15/62;C12N15/63;C12P15/00;C12P17/18;(IPC1-7):A61K31/70;A61K38/12;C12N5/10 |
主分类号 |
A61K38/00 |
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