| 摘要 |
PROBLEM TO BE SOLVED: To provide a TNF-α production inhibitor having high safety, excellent activities for inhibiting the TNF-α production, and useful as a medicine for proliferation, amelioration or therapy of cachexia in cancer or an infectious disease, chronic arthrorheumatism, inflammatory disease, hypertrophic arthritis, systemic lupus erythematosus(SLE), rejection at the time of bone marrow transplantation, multiple organ failure, AIDS, meningitis, hepatitis, type II diabetes and the like, or an animal drug. SOLUTION: This TNF-α production inhibitor, and the agent for the proliferation, the amelioration and the therapy of the disease caused by the abnormal production of the TNF-α contains the kavalactones as an active ingredient. |
