Benzamide derivatives having a vasopressin antagonistic activity

摘要

This invention relates to new benzamide derivatives having a vasopressin antagonistic activity, etc. and represented by general formula (I):whereinR1 is aryl optionally substituted with lower alkoxy, etc.,R2 is lower alkyl, etc.,R3 is hydrogen, etc.,A is NH, etc.,E isetc.,X is -CH=CH-, -CH=N-, or S, andY is a condensed heterocyclic group, etc.,and pharmaceutically acceptable salts thereof, to processes for preparation thereof and to a pharmaceutical composition comprising the same.