发明名称 |
Process for preparing (-)pyridobenzoxazine carboxylic acid derivatives |
摘要 |
Disclosed is a process for preparing optically active (-)pyridobenzoxazine carboxylic acid derivative and pharmaceutically acceptable salt thereof by employing a starting material of (+)ethyl 2-(4-chloro-5-fluoro-2-halo-3-nitobenzoyl)-3-[(1-hydroxypropy-2(s)-yl)amino]acrylate. According to the present invention, optically active (-)pyridobenzoxazine carboxylic acid derivative can be manufactured from low-priced 4-chloro-5-fluorobenzoic acid derivative in a simple and economical manner.
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申请公布号 |
US6316618(B1) |
申请公布日期 |
2001.11.13 |
申请号 |
US20000674323 |
申请日期 |
2000.10.24 |
申请人 |
SAMSUNG ELECTRONICS CO., LTD. |
发明人 |
PARK YOUNG-JUN;LEE HO-SEONG;KIM MIN-HWAN;KIM KYUNG-CHUL |
分类号 |
C07D265/34;A61K31/5383;A61P31/04;C07D215/56;C07D498/06;(IPC1-7):C07D498/06;C07D403/10 |
主分类号 |
C07D265/34 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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