| 发明名称 |
Heterosubstituted pyridine derivatives as PDE 4 inhibitors |
| 摘要 |
The invention encompasses the novel compound of Formula I useful in the treatment of diseases, including asthma, by raising the level of cyclic adenosine-3',5'-monophosphate (cAMP) through the inhibition of phosphodiesterase IV (PDE 4).The invention also encompasses pharmaceutical compositions and methods for treatment.
|
| 申请公布号 |
US6316472(B1) |
申请公布日期 |
2001.11.13 |
| 申请号 |
US20000551046 |
申请日期 |
2000.04.17 |
| 申请人 |
MERCK FROSST CANADA & CO. |
发明人 |
FRENETTE RICHARD;DUCHARME YVES;PRESCOTT SYLVIE |
| 分类号 |
A61K31/44;A61K31/444;A61P1/00;A61P1/04;A61P5/00;A61P7/00;A61P9/00;A61P9/08;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P11/14;A61P11/16;A61P13/02;A61P13/12;A61P17/00;A61P17/02;A61P17/04;A61P17/06;A61P19/00;A61P19/02;A61P21/00;A61P25/00;A61P25/04;A61P25/24;A61P25/28;A61P27/02;A61P27/14;A61P29/00;A61P31/04;A61P31/10;A61P31/12;A61P35/00;A61P37/08;A61P43/00;C07D213/70;C07D213/71;C07D213/89;C07D405/14;C07D409/14;C07D417/14;(IPC1-7):C07D401/06 |
主分类号 |
A61K31/44 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
