发明名称 |
Non-invasive gene targeting to the brain |
摘要 |
Liposomes containing therapeutic genes are conjugated to multiple targeting agents to provide transport of the encapsulated gene across the blood-retinal barrier and the plasma membrane of ocular cells. Once across the blood-retinal barrier and ocular cell membrane, the encapsulated gene expresses the encoded therapeutic agent within the ocular cells to provide diagnosis and/or treatment of disease. |
申请公布号 |
AU5364601(A) |
申请公布日期 |
2001.11.12 |
申请号 |
AU20010053646 |
申请日期 |
2001.04.17 |
申请人 |
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, |
发明人 |
WILLIAM M. PARDRIGE |
分类号 |
A61K9/127;A61K9/51;A61K31/7088;A61K38/00;A61K38/16;A61K38/28;A61K39/395;A61K47/48;A61K48/00;A61P5/48;A61P25/16;A61P35/00;C12N15/88 |
主分类号 |
A61K9/127 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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