Reovirus clearance of ras-mediated neoplastic cells from mixed cellular compositions

摘要

Reovirus can be used to selectively remove ras-mediated neoplasitc cells from a cellular composition. It is of particular interest to purge autographs which may contain neoplastic cells with reovirus before transplanting the autografts back into the recipient, thereby reducing the risk of introducing or reintroducing neoplastic cells into the recipient.