发明名称 |
Use of n-heterocyclic substituted salicylates for inhibition of cellular uptake of cystine |
摘要 |
A method is provided for inhibiting cellular uptake of cystine with a N-heterocyclic substituted salicylate for treatment such as sulfasalazine: Also provided we uses of a N-heterocyclic substituted Salicylate of cancer, for inhibition of cellular uptake of cystine, and for preparation of medicaments for the treatment of cancer or for inhibiting the cellular uptake of cystine. Preferably, the cancer is one which is dependent upon extracellular cystine or cysteine. Also provided are liposomal formulations of N-heterocyclic substituted salicylates. |
申请公布号 |
AU5455901(A) |
申请公布日期 |
2001.11.12 |
申请号 |
AU20010054559 |
申请日期 |
2001.04.27 |
申请人 |
THE UNIVERSITY OF BRITISH COLUMBIA |
发明人 |
PETER WILHELM GOUT;NICHOLAS BRUCHOVSKY |
分类号 |
A61K31/625;A61P35/00;A61P35/02 |
主分类号 |
A61K31/625 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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