发明名称 Produkter til thrombin-inhibitorer
摘要 There is provided compounds of formula I, R<1>O(O)C-CH2-(R)Cgl-Aze-Pab-R<2> wherein R<1> and R<2> have meanings given in the description, which are useful as prodrugs of inhibitors of trypsin-like proteases, such as thrombin, and in particular in the treatment of conditions where inhibition of thrombin is required (eg thrombosis) or as anticoagulants.
申请公布号 DK0995755(T3) 申请公布日期 2001.11.12
申请号 DK19990120315T 申请日期 1996.12.17
申请人 ASTRAZENECA AB 发明人 NYSTROEM, JAN-ERIK;GUSTAFSSON, DAVID;SOERENSEN, HENRIK;SELLEN, MIKAEL
分类号 A61K38/55;A61K;A61K31/00;A61K38/00;A61K38/05;A61K38/06;A61P7/00;A61P7/02;A61P9/10;A61P43/00;C07D;C07D487/04;C07D491/04;C07D495/04;C07K;C07K1/02;C07K5/00;C07K5/02;C07K5/06;C07K5/065;C12N9/99 主分类号 A61K38/55
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