Cephalosporins containing in position 7 a substituted benzyloxyimino radical, processes for their preparation and intermediates for their preparation, their use as medicaments

摘要

Syn isomer of cpds. of formula (I), and their salts, are new. In (I), R1-R3, R5 = H, halo, OH, 1-4C alkyl (opt. substd. by halo, 1-4C alkyloxy, SH etc.); R4 = OH or 1-8C acyloxy; R7 = H or (1-3C alkyloxy)carbonyl; A = e.g. H, an equivalent of alkali(ne earth) metal, Mg, ammonium or aminated organic base etc.; or CO2A = CO2-; wavy line shows that CH2R6 can be in E- or Z-position; R6 = e.g. quat. ammonium or gp. of formula (i); X = CH2, NH, O or S; and Y, T, U, V, W and Z = CH or N; with the provisos.