Transcriptionally regulated g protein-coupled receptor g2a

摘要

A G protien-coupled receptor (GPCR), called G2A, whose expression is regulated and functions at the G2/M checkpoint to ensure properly controlled duplication of hematopietic cells. The receptor is found predominantly in hematopietic cells and tissues and functions as a tumor suppressor gene, induces cell cycle arrest and integrates diverse signals by modulation of cytoskeletal architecture.