摘要 |
<p>Disclosed are methods for treating or preventing abnormal bone resorption in mammals while minimizing the occurrence of adverse gastrointestinal effects. Also disclosed are pharmaceutical compositions and kits for carrying out the therapeutic methods using bisphosphonates selected from the group consisting of alendronate, cimadronate, clodronate, tiludronate, etridronate, ibandronate, risedronate, piridronate, pamidronate, zolendronate, pharmatheutically acceptable salts thereof, and mixtures thereof.</p> |