Optically active quaternary ammonium salt with axial asymmetry, process for producing the same, and application to asymmetric synthesis of alpha-amino acid derivative

摘要

A novel optically active quarternary ammonium salt with an axial chirality is provided. The quarternary ammonium salt can act as a phase-transfer catalyst to convert glycine derivatives into optically active alpha-amino acid derivatives by stereoselectively alkylating the glycine derivatives. Furthermore, according to the present invention, intermediates useful for producing the novel quarternary ammonium can be produced.