发明名称 Arylpiperazinyl-cyclohexyl indole derivatives for the treatment of depression
摘要 Compounds are provided which are useful for the treatment of serotonin-affected neurological disorders which compriseWherein:R1, R2 and R3 are each, independently, hydrogen, halogen, CF3, alkyl, alkoxy, MeSO2, or together can form a 5-7 membered carbocyclic or heterocyclic ring;R4 is hydrogen, halogen, or alkyl;R5 is hydrogen, alkyl, alkylaryl, or aryl;R6 is hydrogen, halogen, CF3, CN, carbamide, or alkoxy;X1, X2 and X3 are each carbon or one of X1, X2 or X3 may be nitrogen;Y is carbon or nitrogen; andZ is carbon or nitrogen; orpharmaceutically acceptable salts thereof.
申请公布号 US6313126(B1) 申请公布日期 2001.11.06
申请号 US19990476254 申请日期 1999.12.30
申请人 AMERICAN HOME PRODUCTS CORP 发明人 MEWSHAW RICHARD E.;ZHOU PING;ZHOU DAHUI;MEAGHER KRISTIN L.;ASSELIN MAGDA;EVRARD DEBORAH A.;GILBERT ADAM M.
分类号 C07D209/14;C07D209/34;C07D401/08;C07D401/12;C07D403/12;C07D405/12;C07D471/04;(IPC1-7):A61K31/496;A61K31/498;C07D401/14;C07D403/14;C07D405/14 主分类号 C07D209/14
代理机构 代理人
主权项
地址