发明名称 |
BENZOYLPYRIDAZINE DERIVATIVE, PROCESS FOR THE PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITION CONTAINING SAME |
摘要 |
<p>A group of compounds of, the preparation of, and the methods of use of benzoylpyridazine derivatives and the physiologically acceptable salts and solvates thereof, which have valuable pharmacological properties while well tolerated. They selectively inhibit phosphodiesterase IV with an intracellular increase in the CAMP level, and have an inhibitory effect on the formation of tumor necrosis factor.</p> |
申请公布号 |
SK5782001(A3) |
申请公布日期 |
2001.11.06 |
申请号 |
SK20010000578 |
申请日期 |
1999.10.23 |
申请人 |
MERCK PATENT GMBH |
发明人 |
JONAS ROCHUS;WOLF MICHAEL;KLUXEN FRANZ-WERNER |
分类号 |
A61K31/50;A61K31/501;A61P1/04;A61P3/10;A61P9/10;A61P11/06;A61P19/02;A61P19/08;A61P19/10;A61P25/00;A61P29/00;A61P31/18;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D237/04;C07D273/04;C07D401/12;(IPC1-7):C07D273/04 |
主分类号 |
A61K31/50 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|