发明名称 Purification process
摘要 Crystalline 2-(amninothiazol-4-yl)-2-(tert.butoxycarbonylmethoxyimino)acetic acid-S-mercapto-benzo-thiazolylester in form of an N,N-dimethylacetamide solvate; a crystalline salt of a 7-[2-(aminothiazol-4-yl)-2-(carboxymethoxyimino)acetamido]-3-vinyl-3-cephem-4-carboxylic acid with an amine of formula N(R1)(R2)(R3), wherein R1, R2, and R3 have various meanings, a crystalline sulphuric acid addition salt of a 7-[2-(2-aminothiazol-4-yl)-2-carboxymethoxyimino)acetamido]-3-vinyl-3-cephem-4-carboxylic acid; and the use of these salts in the production of cefixime, e.g. in form of a trihydrate.
申请公布号 US6313289(B1) 申请公布日期 2001.11.06
申请号 US19990341542 申请日期 1999.08.04
申请人 BIOCHEMIE GESELLSCHAFT M.B.H. 发明人 LUDESCHER JOHANNES;MILLER LUDWIG;STURM HUBERT;VEIT WERNER;DECRISTOFORO MARTIN;WOLF SIEGFRIED
分类号 C07D501/00;C07D501/04;C07D501/22;(IPC1-7):C07D501/04;C07D417/12 主分类号 C07D501/00
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