| 摘要 |
<p>There is provided heterocyclic compounds of the following formula (I): in which, A is optionally substituted alkyl group, optionally substituted aryl group or optionally substituted heterocyclic group; B?1 and B2¿ are, hydrogen atom, alkyl group or hydroxyl group; or combined together to represent carbonyl group; X is oxygen atom, sulfur atom, carbon atom or nitrogen atom; dotted line shows either presence or absence of bond; n is integer of 1 or 2; and the group -X-Y- represents optionally substituted alkylene or cyclic alkenylene bond; or a pharmaceutically acceptable salt thereof. These compounds have good affinity for α4β2 nicotinic acetylcholine receptors and activate the same to thereby exert a preventive or therapeutic effect on cerebral dysfunction.11</p> |
