| 发明名称 |
COMBRETASTATIN A-1 PHOSPHATE AND COMBRETASTATIN B-1 PHOSPHATE PRODRUGS |
| 摘要 |
The present invention relates to the syntheses and structural elucidation of Combretastatin A1-Phosphate Prodrugs and Combretastatin B1-Phosphate Prodrug s and the utilization of those prodrugs in the treatment of neoplastic disease s. The prodrugs described herein have the structure: Combretastin A-1 Phosphate Prodrug (I) and Combretastin B-1 Phosphate Prodrug (II).
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| 申请公布号 |
CA2407675(A1) |
申请公布日期 |
2001.11.01 |
| 申请号 |
CA20012407675 |
申请日期 |
2001.04.27 |
| 申请人 |
ARIZONA BOARD OF REGENTS, A BODY CORPORATE OF THE STATE OF ARIZONA, ACTI ACT |
发明人 |
LIPPERT, JOHN W., III;PETTIT, GEORGE R. |
| 分类号 |
A61K47/48;C07C255/43;C07D213/82;C07D217/20;C07D295/02;C07D295/027;C07D453/04;C07F9/12;(IPC1-7):C07F9/02;A01N57/00;C07F9/22;A01N57/26;C07F9/28;A61K31/66;A61K31/685 |
主分类号 |
A61K47/48 |
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