发明名称 |
METHODS AND COMPOSITIONS FOR ELECITING AN IMMUNE RESPONSE |
摘要 |
The invention provides methods and compositions useful for inducing or enhancing an immune response in a human or non-human animal. In an embodiment, the method involves administering an antigen-presenting cell chemotaxin, such as a chemokine polypeptide or variant thereof, optionally with administration of an antigen. In some embodiments, the chemokine or variant is chemotactic for dendritic cells and/or macrophages, but not chemotactic for one or more of neutrophils, T-lymphocytes, monocytes, or eosinophils. In an embodiment, the chemokine or variant is a chemotaxin for immature but not mature dendritic cells. |
申请公布号 |
WO0180887(A2) |
申请公布日期 |
2001.11.01 |
申请号 |
WO2001US12162 |
申请日期 |
2001.04.12 |
申请人 |
CHEMOCENTRYX, INC.;SCHALL, THOMAS, J.;TALBOT, DALE |
发明人 |
SCHALL, THOMAS, J.;TALBOT, DALE |
分类号 |
A61K38/00;A61K39/39;A61P37/04 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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