发明名称 |
4-BENZYL-1-[2-(4-HYDROXY-PHENOXY)-ETHYL]-PIPERIDINE-3,4-DIOL |
摘要 |
The invention relates to a compound of formula (I), its R,R- and S,S- enantiomeres and to their pharmaceutically acceptable acid addition salts. T he compound of formula (I) and its R,R- and S,S-enantiomeres may be used as medicaments for the treatment of diseases, wherein the therapeutic indicatio ns include acute forms of neurodegeneration caused by stroke or brain trauma; chronic forms of neurodegeneration such as Alzheimer's disease, Parkinson's disease, Huntington's disease or ALS (amyotrophic lateral sclerosis); neurodegeneration associated with bacterial or viral infections, and disease s such as schizophrenia, anxiety, depression and chronic/acute pain.
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申请公布号 |
CA2407345(A1) |
申请公布日期 |
2001.11.01 |
申请号 |
CA20012407345 |
申请日期 |
2001.04.17 |
申请人 |
F. HOFFMANN-LA ROCHE AG |
发明人 |
JAESCHKE, GEORG;PINARD, EMMANUEL;BUETTELMANN, BERND;HEITZ NEIDHART, MARIE-PAULE;ALANINE, ALEXANDER;WYLER, RENE |
分类号 |
C07D211/50;A61K31/445;A61P21/04;A61P25/06;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P29/00;C07D211/48;(IPC1-7):C07D211/50;A61K31/44 |
主分类号 |
C07D211/50 |
代理机构 |
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代理人 |
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