发明名称 |
PRODUCT AND PROCESS FOR REGULATION OF T CELL RESPONSES |
摘要 |
Disclosed is a method for increasing a memory T cell response by administering to a patient a composition that increases the activity of IL-15 and that decreases the activity of IL-2. Also disclosed is a vaccine adjuvant useful for increasing memory T cell responses. A method for inhibiting undesirable immune responses, such as autoimmune responses, is also disclosed, as is a composition useful in such a method. The composition includes a compound that increases the activity of IL-2 and in one embodiment, further includes a compound that decreases the activity of IL-15. |
申请公布号 |
WO0180889(A1) |
申请公布日期 |
2001.11.01 |
申请号 |
WO2001US13861 |
申请日期 |
2001.04.26 |
申请人 |
NATIONAL JEWISH MEDICAL AND RESEARCH CENTER |
发明人 |
MARRACK, PHILLIPA;KAPPLER, JOHN, W.;KU, CHIA, CHI;MURAKAMI, MASAAKI;SAKAMOTO, AKEMI |
分类号 |
A61K9/00;A61K38/00;A61K38/20;A61K39/39;A61K39/395;C07K16/24;C07K16/28;C12P21/08;(IPC1-7):A61K39/395;A61K39/40;A61K39/42;A61K45/00;A61K47/00;C07K16/00 |
主分类号 |
A61K9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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