发明名称 Method for prophylaxis and treatment of diabetic complications with 4[alpha-hydroxy-2-methyl-5(1-imidazolyl)benzyl]-3,5-dimethylbenzoic acid and derivatives
摘要 The present invention relates to an agent for the prophylaxis and treatment of diabetic complications comprising, as an active ingredient, 4-[alpha-hydroxy-2-methyl-5-(1-imidazolyl)benzyl]-3,5-dimethylbenzoic acid, an optically active compound thereof or a pharmaceutically acceptable salt thereof. The present invention fuher relates to a method for the prophylaxis and treatment of diabetic complications comprising administering an effective amount of this compound. The medicament of the present invention is useful for the prophylaxis and treatment of diabetic complications, namely, diabetic neuropathy, nephropathy, ophthalimopathy, arteriosclerosis and the like. The action of the drug is long-lasting for very small doses and a single administration a day is sufficient.
申请公布号 US2001036957(A1) 申请公布日期 2001.11.01
申请号 US20010850000 申请日期 2001.05.08
申请人 发明人 HAYASHI YOSHIHARU;GOTO NOBUHARU
分类号 A61K31/415;A61K31/4164;A61P3/10;C07D233/54;C07D233/60;C07D521/00;(IPC1-7):A61K31/416 主分类号 A61K31/415
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