发明名称 |
Pestivirus mutants and vaccines containing the same |
摘要 |
<p>The present invention is directed to attenuated pestivirus mutants, which have a reduced ability to replicate as exhibited by a small plaque size. The mutations are in the 5' nontranslated region of the viral genome. These mutant viruses are useful as live vaccines in the control of bovine viral diarrhea, border disease and classical swine fever.</p> |
申请公布号 |
EP1149901(A1) |
申请公布日期 |
2001.10.31 |
申请号 |
EP20010201388 |
申请日期 |
2001.04.17 |
申请人 |
AKZO NOBEL N.V. |
发明人 |
THIEL, HEINZ-JUERGEN;BECHER, PAUL;ORLICH, MICHAELA |
分类号 |
C12N15/09;A61K39/12;A61K39/135;A61K39/155;A61K39/187;A61K39/20;A61K39/215;A61K39/245;A61P31/12;A61P31/14;A61P31/20;A61P31/22;C07K14/18;C12N7/04;C12N7/08;(IPC1-7):C12N7/04 |
主分类号 |
C12N15/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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