发明名称 Ligand for herpes simplex virus entry mediator and methods of use
摘要 A novel polypeptide ligand, p30, or LIGHT, for herpes virus entry mediator, HVEM, is provided. p30 is useful for modulating immune responses and in inhibiting infection and/or subsequent proliferation by herpes virus. HVEM fusion proteins are also provided. Methods for treating subjects with lymphoid cell disorders, tumors, autoimmune diseases, inflammatory disorders of those having or suspected of having a herpes virus infection, utilizing p30 and the fusion proteins of the invention, are also provided.
申请公布号 AU5338701(A) 申请公布日期 2001.10.30
申请号 AU20010053387 申请日期 2001.04.11
申请人 LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY 发明人 CARL F WARE
分类号 A61K38/00;A61K31/713;A61K35/76;A61K38/17;A61K39/395;A61P3/10;A61P19/02;A61P25/00;A61P29/00;A61P31/12;A61P35/00;A61P35/02;A61P37/02;C07K14/47;C07K14/705;C07K16/08;C07K19/00;C12N15/12;C12N15/62 主分类号 A61K38/00
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