[3H,7H]THIAZOLO[3,4-A]PYRIDINES WITH ANTIASTHMATIC AND A ANTIINFLAMMATORY ACTIONS ON THE RESPIRATORY TRACT

摘要

Compounds of formula (I) wherein R is an alkyl group; R1 is a cyano carboxy, alkoxycarbonyl, aminocarbonyl or hy- droxylaminocarbonyl group; R2 is substituted or unsubstituted phenyl, (C3-C7 )- cycloalkyl, .alpha.-, .beta.- or .gamma.-pyridyl or a benzohe- terocyclic ring; R3 is carboxy or carboalkoxy; Y is a group of the formula COOX; -NHCOA; -NCO; -COA; -CONHOR e; -OCOA; A; -CO-CH2-CO-R f; -NHCSA; -OCSA; (a); X is hydrogen, alkyl or a succinimidyl group; A is a cyclic of acyclic amino group; and n is 1 or 2; having pharmacological characteristics which render them useful in the treatment of inflam- matory conditions of the respiratory tract and asthmatic conditions.