发明名称 Method of preventing neuronal death
摘要 Disclosed is a method for preventing neuronal cell death subsequent to an injury to neuronal tissue, particularly central nervous tissue exposed to an ischemic or hypoxic event, to trauma or to a chronic neurodegenerative disorder. The method includes exposing the cells to a glutaminase inhibitor that is relatively impermeant to healthy, intact cell membranes, and which is preferably a specific inhibitor of the form of glutaminase that is widely present in brain tissue.
申请公布号 US6310093(B1) 申请公布日期 2001.10.30
申请号 US19980141881 申请日期 1998.08.27
申请人 ELAN PHARMACEUTICALS, INC. 发明人 NEWCOMB ROBERT
分类号 A61K31/00;A61K31/185;A61K31/198;(IPC1-7):A61K31/195;A01N55/06 主分类号 A61K31/00
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