发明名称 |
Gruppe B-streptococcus type II- og type V-polysaccharid-protein-konjugat-vacciner |
摘要 |
<p>Antigenic conjugate (A) comprising (1) a capsular polysaccharide (CPS) of type II or V G.B Streptococcus and (2) a protein (I) linked to 2 or more side chains, terminating in sialic acid residues, of CPS through a sec. amino bond is new. CPS has mol.wt. at least 5000. Pref. 5-50% of terminal sialic acid residues are available for linkage to (I); esp. about 7% or 25% for type II or type V CPS respectively. Partic. (I) are tetanus or diphtheria toxoid, or cross reactive material 197.</p> |
申请公布号 |
DK0667787(T3) |
申请公布日期 |
2001.10.29 |
申请号 |
DK19930922357T |
申请日期 |
1993.09.24 |
申请人 |
NATIONAL RESEARCH COUNCIL OF CANADA;BRIGHAM AND WOMEN'S HOSPITAL, INC. |
发明人 |
JENNINGS, HAROLD J.;KASPER, DENNIS L. |
分类号 |
A61K39/09;A61K;A61K39/102;A61K39/108;A61K39/116;A61K39/385;A61K47/48;A61P3/10;A61P31/04;A61P35/00;A61P37/04;C07K14/315;C12P21/00;(IPC1-7):A61K39/09 |
主分类号 |
A61K39/09 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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