| 发明名称 |
PROCESS FOR THE PREPARATION OF THE MESYLATE SALT TRIHYDRATE OF 1-(4-HYDROXYPHENYL)-2-(4-HYDROXY-4-PHENYLPIPERIDIN-1-YL)-1-PROPANOL |
| 摘要 |
The present invention is directed to a process for the preparation of the mesylate trihydrate of the (1S,2S)-1-(4-hydroxyphenyl)-2-(4-hydroxy-4-phenylpiperidin -1- yl)-1-propanol compound having the formula (I): The present invention is also further comprises a process for enantiomeric resolution and isolation of the (D)-(-)-tartrate salt of the compound of the formula (I).</ SDOAB>
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| 申请公布号 |
CA2345582(A1) |
申请公布日期 |
2001.10.28 |
| 申请号 |
CA20012345582 |
申请日期 |
2001.04.26 |
| 申请人 |
PFIZER PRODUCTS INC. |
发明人 |
SINAY, TERRY GENE JR.;WALINSKY, STANLEY WALTER;RAINVILLE, JOSEPH PHILIP |
| 分类号 |
A61K31/445;A61K31/451;A61P3/08;A61P9/10;A61P13/02;A61P21/00;A61P21/02;A61P25/00;A61P25/04;A61P25/06;A61P25/08;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/28;A61P25/30;A61P25/32;A61P29/00;A61P31/18;A61P43/00;C07B57/00;C07D211/52;(IPC1-7):C07D211/52 |
主分类号 |
A61K31/445 |
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