发明名称 Treatment of diabetes mellitus with 5-[4-[2-(N-methyl-N-(2- pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione (2-12 mg) and an alpha-glucosidase inhibitor antihyperglycemic agent
摘要 A method for the treatment of diabetes mellitus and associated conditions in a mammal, which comprises administering an effective non-toxic and pharmaceutically acceptable amount of an insulin sensitiser and an alpha-glucosidase inhibitor antihyperglycaemic agent, to a mammal in need thereof. The insulin sinsitiser is 5-[4-[2-(N-methyl-N-(2- pyridyl)amino) ethoxy]benzyl]thiazolidine-2,4-dione (Compound (I) of EP 0306228) and is present in the medicament in amounts of 2 to 12 mg. The alpha-glucosidase inhibitor could be acarbose, emiglitate or miglitol.
申请公布号 NZ501345(A) 申请公布日期 2001.10.26
申请号 NZ19980501345 申请日期 1998.07.15
申请人 SMITHKLINE BEECHAM PLC 发明人 SMITH, STEPHEN ALISTAIR
分类号 A61K31/426;A61K31/427;A61K31/44;A61K31/4439;A61K31/445;A61K31/7008;A61K31/702;A61K31/7036;A61K45/06;A61P3/10;(IPC1-7):A61K31/44;A61K31/715;A61K31/70 主分类号 A61K31/426
代理机构 代理人
主权项
地址