Ophthalmic compositions containing a divalent salt and a non steroidal anti-inflammatory drug as a precipitate

摘要

An ophthalmic composition containing a divalent salt and a non-steroidal anti-inflammatory agent as a precipitate is disclosed. The composition reduces or eliminates the risk of stinging and burning the eye from topical application. Additionally a preservative system comprising a perborate salt, a polyphosphonic acid peroxy stabilizer and EDTA provides stable preservation of a variety of aqueous ophthalmic compositions.