Porous greasy or non-greasy hydroxyapatite ceramic particles and a greasy, oily or sticky excipient as carriers for drug substances

摘要

A dry, solid drug delivery composition for oral administration. The composition contains (i) a greasy, oily, or sticky substance and a pharmaceutically active substance, or (ii) a pharmaceutically active substance which itself is greasy, oily, or sticky. The composition is characterized by having a plurality of porous inorganic particles composed of ceramic hydroxyapaptite having a diameter of from 5 to 150 mm, having fast release characteristics, and incorporating 15-40 wt% of (i) or (ii).