A COMPLEX BETWEEN FOLIC ACID AND POLYSACCHARIDES, ITS PREPARATION METHOD AND A PHARMACEUTICAL COMPOSITION COMPRISING SAID COMPLEX AS ACTIVE COMPONENT

摘要

This invention relates to a complex between folic acid and polysaccharides and its preparation method, especially relates to a complex between folic acid and dextran, its preparation method and a pharmaceutical composition comprising said complex as active component, and also the use of such complex in anti-tumor. The general formula of the complex is as follows: (X)n-Y, wherein X can be the same or different, and is selected from folic acid and its derivatives or other substances targeting cells through FR of the cell membrane, Y is polysaccharides and n >/=1.