| 摘要 |
<p>The invention describes a method for obtaining glycosides from monosaccharide N-acetyl-D-glucosamine derivatives and a research on its glioblastoma inhibiting and cytotoxic activity. Glycosides of general formula (I) have been prepared from monosaccharide N-acetyl-D-glucosamine, wherein aglycone R1 is a hydrophobic radical, preferably a linear or branched hydrocarbonated 8-16 carbon chain. The invention also relates to the use of glycosides of N-acetyl-6-O-[2,2-bis(hydroxymethyl)-3-hydroxypropyl]-D-glucosamine for inhibiting human glioma cultures.</p> |
