| 摘要 |
<p>Compounds represented by the general formula (1), prodrugs thereof or pharmaceutically acceptable salts thereof which have an effect of inhibiting poly(ADP-ribose)polymerase (PARP) and are useful as remedies for diseases caused by the accelerated PARP activity such as brain ischemic disorders in said formula (1), -X1-X2- represents C(=O)-N(R7)- or -C(R8)=N- (wherein R7 represents hydrogen, optionally substituted alkyl, etc.; and R8 represents halogeno, etc.); R?1, R2 and R3¿ independently represent each hydrogen, optionally substituted alkyl, etc.; and R4 represents optionally substituted alkylene.</p> |
