POLYAMIDE NUCLEIC ACID DERIVATIVES, AGENTS AND METHODS FOR PRODUCING THEM

摘要

The invention relates to PNA derivatives that carry one or more phosphoryl groups at the C terminus or at the C and N terminus of the PNA backbone, sai d phosphoryl groups optionally carrying one or more marker groups, or groups f or cross-linking, or groups that promote the intracellular uptake, or groups th at improve the binding affinity of the PNA derivative to nucleic acids. The invention further relates to a method for producing the above PNA derivative s and to the use thereof as a medicament or diagnostic agent.