21953, A NOVEL HUMAN PROLYL OLIGOPEPTIDASE FAMILY MEMBER AND USES THEREOF

摘要

The invention provides isolated nucleic acids molecules, designated 21953 nucleic acid molecules, which encode novel prolyl oligopeptidase members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 21953 nucleic acid molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 21953 gene has been introduced or disrupted. The invention still further provides isolated 21953 proteins, fusion proteins, antigenic pepides and anti-21953 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.