发明名称 |
BIOSENSOR AND RELATED METHOD |
摘要 |
A microscale biosensor for use in the detection of target biological substances including molecules and cells is a microfluidic system with integrated electronics, inlet-outlet ports and interface schemes, high sensitivity detection of pathogen specificity, and processing of biological materials at semiconductor interfaces (Fig. 1). A fabrication process includ es an all top-side processing for the formation of fluidic channels, planar fluidic interface ports, integrated metal electrodes for impedance measurements, and a glass cover sealing the non-planar topography of the chi p using spin-on-glass as an intermediate bonding layer. Detection sensitivity is enhanced by small fluid volumes, use of a low-conductivity buffer, and electrical magnitude or phase measurements over a range of frequencies.</SDO AB>
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申请公布号 |
CA2406133(A1) |
申请公布日期 |
2001.10.25 |
申请号 |
CA20012406133 |
申请日期 |
2001.03.26 |
申请人 |
PURDUE RESEARCH FOUNDATION |
发明人 |
SARIKAYA, AYDA;ROBINSON, J. PAUL;GOMEZ, RAFAEL;BHUNIA, ARUN K.;LADISCH, MICHAEL R.;BASHIR, RASHID |
分类号 |
G01N33/543;G01N33/569;(IPC1-7):C12Q1/04;C12M3/00;C12Q1/02;C12M1/34 |
主分类号 |
G01N33/543 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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