发明名称 |
DISSOCIATED PILI, THEIR PRODUCTION AND USE |
摘要 |
A method of producing pili and vaccines containing pili is described using bacteria harboring mutations that facilitate detachment of pili from the bacteria. Wild type pili have known immunoprotective effects in treating urinary tract infections. The mutant pili produced by this method are also shown to have such immunoprotective effects. Therefore, the pili may be used to make vaccines for treating urinary tract infections. |
申请公布号 |
WO0178773(A2) |
申请公布日期 |
2001.10.25 |
申请号 |
WO2001US11919 |
申请日期 |
2001.04.12 |
申请人 |
O'HANLEY, PETER;DENICH, KENNETH |
发明人 |
DENICH, KENNETH |
分类号 |
A61K39/00;A61P31/04 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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