| 摘要 |
<p>The invention provides the crystal structure of Methanobacterium thermoautotrophicum RmlC (MT RmlC) and identifies the active site thereof. The crystal structure can be used to determine the crystal structure of homologues, analogues, mutants and co-complexes of MT RmlC and to identify and design inhibitors to RmlC. The present invention has applicability in identifying and designing anti-bacterial agents and the treatment of bacterial infections.</p> |
