发明名称 3'-OR 2'-HYDROXYMETHYL SUBSTITUTED NUCLEOSIDE DERIVATIVES FOR TREATMENT OF HEPATITIS VIRUS INFECTIONS
摘要 The present invention relates to a composition for and a method of treating hepatitis B virus (HBV) infection, hepatitis C virus (HCV) infection, hepatitis D virus (HDV) infection or a proliferative disorder in a patient using an effective amount of a compound selected from the group consisting o f formulas (I)-(IV) below and mixtures of two or more thereof, wherein the substituents are as defined herein. Pharmaceutical compositions comprising these compounds in combination with other HBV, HCV, or HDV agents is also disclosed.
申请公布号 CA2404639(A1) 申请公布日期 2001.10.25
申请号 CA20012404639 申请日期 2001.04.13
申请人 PHARMASSET, LTD. 发明人 WATANABE, KYOICHI A.;PAI, BALAKRISHNA S.
分类号 A61K31/13;A61K31/513;A61K31/52;A61K31/5383;A61K31/662;A61K31/7068;A61K31/7072;A61K31/7076;A61K31/712;A61K38/00;A61K38/21;A61P1/16;A61P31/12;A61P31/14;A61P31/18;A61P31/20;A61P35/00;A61P35/02;C07D405/04;C07D413/04;C07D493/04;C07H19/06;C07H19/10;C07H19/16;C07H19/20;(IPC1-7):A61K31/706;A61K31/707;A61K31/708 主分类号 A61K31/13
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