发明名称 |
A PROCESS FOR THE PREPARATION OF DECAHYDRO-2A,4A,6A,8A-TETRAAZACYCLOPENT[FG]ACENAPHTHYLENE AND FUNCTIONALIZED DERIVATIVES |
摘要 |
A process for the preparation of compound of formula (IA), decahedra-2a,4a,6a,8a-tetraazaccyclopent[fg]acenaphthylene and the corresponding functionalised compounds of general formula (I), which comprises 2 steps; a) the preparation of compounds of general formula (III) and b) subsequent reduction thereof. R are both hydrogen, or one is hydrogen and the other is a straight or branched C1-C4 alkyl group, optionally substituted with one or more -OPg- protected groups, in which Pg is a hydroxy - protecting group. Y1 or Y2 is -CH2-CH2 and the other is -Co-Co- or a group of formula -COCHR, wherein R has the meaning defined above. |
申请公布号 |
WO0179207(A2) |
申请公布日期 |
2001.10.25 |
申请号 |
WO2001EP04092 |
申请日期 |
2001.04.10 |
申请人 |
BRACCO INTERNATIONAL BV;ARGESE, MARIA;BROCCHETTA, MARINO;MANFREDI, GIUSEPPE;REBASTI, FABRIZIO;RIPA, GIORGIO |
发明人 |
ARGESE, MARIA;BROCCHETTA, MARINO;MANFREDI, GIUSEPPE;REBASTI, FABRIZIO;RIPA, GIORGIO |
分类号 |
C07D487/06;C07B61/00;C07D487/22 |
主分类号 |
C07D487/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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