| 发明名称 |
Metalloproteinase inhibitors, pharmaceutical compositions containing them, and their use |
| 摘要 |
The present invention is directed to compound of the formula I:wherein R1, R2, R3, R4, R 5, X, Y, andare as defined herein.These compounds are useful for inhibiting the activity of a metalloproteinase by contacting the metalloproteinase with an effective amount of the inventive compounds.
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| 申请公布号 |
US6306892(B1) |
申请公布日期 |
2001.10.23 |
| 申请号 |
US20000598208 |
申请日期 |
2000.06.21 |
| 申请人 |
AGOURON PHARMACEUTICALS, INC.;SYNTEX INC. |
发明人 |
BENDER STEVEN L.;CASTELHANO ARLINDO L.;CHONG WESLEY K. M.;ABREO MELWYN A.;BILLEDEAU ROLAND J.;CHEN JIAN JEFFREY;DEAL JUDITH G. |
| 分类号 |
A61K38/00;C07D207/32;C07D207/327;C07D207/337;C07D231/12;C07D233/54;C07D307/54;C07D333/24;C07D401/10;C07D401/12;C07D405/12;C07D405/14;C07D487/08;C07D498/08;C07D521/00;C07K5/06;C07K5/072;(IPC1-7):A61K31/381;C07D333/04 |
主分类号 |
A61K38/00 |
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