发明名称 |
Dye-labeled protein conjugate and method for preparing the same |
摘要 |
The present invention provides a dye-labeled protein conjugate in which a protein conjugate is labeled with a large number of dye molecules. In the dye-labeled protein conjugate, a protein conjugate that includes a protein and an antibody bound thereto via a disulfide bond is labeled with a cyanine dye represented by the formula (1) or the formula (2) given below:where R1 and R2 denote hydrogen or an alkyl group, X denotes a halogen, M denotes hydrogen or an alkali metal, and n represents an integer in a range of 1 to 4.
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申请公布号 |
US6307029(B1) |
申请公布日期 |
2001.10.23 |
申请号 |
US19990311147 |
申请日期 |
1999.05.13 |
申请人 |
MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. |
发明人 |
SHIGETOU NOBUYUKI;MIYAZAKI JINSEI;NAKAYAMA HIROSHI |
分类号 |
G01N33/531;G01N33/532;(IPC1-7):C07K17/02;C07K1/13;G01N33/533 |
主分类号 |
G01N33/531 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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