SUBSTITUTED TRIAZOLOPYRIDAZINES

摘要

This invention is directed to a group of compounds which are acyl derivatives of amino substituted triazolopyridazines. They are prepared by the reaction of an aminotriazolopyridazine or an aminotriazolophthalazine with an appropriate acid chloride. These compounds possess bronchodilating and anti-allergenic activity and are of the following general formula: wherein R7 and R8 are each independently H or CH3, or R7 and R8 together are -CH2CH2CH2CH2-; and when R7 and R8 are together -CH2CH2CH2CH2-, then, R3 is <IMGS> or -NH2 ; and when R7 and R8 are each independently H or CH3, then R3 is or -2-