发明名称 |
Inhibitors of prenyl-protein transferase |
摘要 |
The present invention is directed to peptidomimetic macrocyclic compounds which inhibit prenyl-protein transferase and the prenylation of the oncogene protein Ras. The invention is further directed to chemotherapeutic compositions containing the compounds of this invention and methods for inhibiting prenyl-protein transferase and the prenylation of the oncogene protein Ras. |
申请公布号 |
AU5324601(A) |
申请公布日期 |
2001.10.23 |
申请号 |
AU20010053246 |
申请日期 |
2001.04.06 |
申请人 |
MERCK AND CO., INC. |
发明人 |
CRAIG A. STUMP;THERESA M. WILLIAMS;DIEM N. NGUYEN |
分类号 |
A61P35/00;C07D498/22;C07D513/22 |
主分类号 |
A61P35/00 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|