摘要 |
Pharmaceutical compositions comprising a compound of formula (I), in which R is optionnally substituted phenyl; C3-8 cycloalkyl; C5-8 cylcoalkenyl; C1-8 alkyl which may be straight or branched; C2-8 alkenyl which may be straight or branched; 5- or 6- membered heterocyclyl; or optionally substituted phenyl C 1- 4 alkyl, each of Y and Z, which may be the same or different, is oxygen or sulphur; and X is a bond, -CH2-, or oxygen; and at least one other anthelmintically active compound which is an avermectin or milbemycin, are useful in the treatment o f helminthiasis.
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