| 摘要 |
A pharmaceutical agent comprising an ascorbic acid, a derivative thereof or a salt thereof (ascorbic acids) as an active ingredient, for selectively inducing apoptosis of unnecessary or pathogenic cells to thereby prevent and/or treat diseases caused by said cells; a method for the prophylaxis and/or treatment of diseases caused by unnecessary or pathogenic cells, comprising selectively inducing apoptosis of said cells by the use of ascorbic acids; and use of ascorbic acids for the production of a pharmaceutical agent for selectively inducing apoptosis of unnecessary or pathogenic cells to thereby prevent and/or treat diseases caused by said cells. The ascorbic acids are low toxic and selectively induce apoptosis of unnecessary or pathogenic cells. Therefore, they are useful for the prophylaxis and/or treatment of the diseases caused by said cells. For example, they serve for use as anticancer agents and carcinostatic agents, as well as for the prophylaxis and/or treatment of many diseases caused by various viral infections. In particular, since they selectively induce apoptosis of unnecessary or pathogenic cells, they are useful for the prophylaxis and/or treatment of HIV viral infections and the prophylaxis and/or treatment of acquired immune deficiency syndrome (AIDS).
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