| 发明名称 |
Chemically-modified myelopoietin conjugates |
| 摘要 |
The present invention provides a chemically modified Myelopoietin (MPO) prepared by binding a water soluble polymer to the protein. The chemically-modified protein according to the present invention may have a much longer lasting neutrophil-increasing activity than that of the un-modified MPO, enabling reduced dose and scheduling opportunities. |
| 申请公布号 |
AU8930701(A) |
申请公布日期 |
2001.10.23 |
| 申请号 |
AU20010089307 |
申请日期 |
2001.04.06 |
| 申请人 |
PHARMACIA CORPORATION |
发明人 |
RORY FINN;YATIN GOKARN;ROBERT HILLS;PETER NICASTRO;HONG QI;KURT SEDO;NED SIEGEL;SMITH WALTER |
| 分类号 |
A61K38/00;A61K47/48;A61P7/00;A61P37/02;A61P37/06;C07K14/535;C07K14/54 |
主分类号 |
A61K38/00 |
| 代理机构 |
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