| 摘要 |
The present invention provide a therapeutic agent for dermatitis, particularly a therapeutic agent for atopic dermatitis, having high safety and showing little adverse reaction such as steroidal agent. The present invention relates to a therapeutic agent for dermatitis, particularly a therapeutic agent for atopic dermatitis, containing a compound represented by the following formula (I) or a pharmaceutically acceptable salt or hydrate thereof as an effective ingredient. <CHEM> (In the formula, R is hydrogen or halogen.) The therapeutic agent for dermatitis according to the present invention significantly and dose-dependently suppressed the antigen-induced swelling reaction in ear of mouse recognized as an animal model for atopic dermatitis. Also, the agent suppressed the antigen-induced flare reaction of mice occurred with the swelling reaction. In addition, the adverse reaction to the skin was not observed. The therapeutic agent for dermatitis of this invention is, therefore, is very useful as a drug for atopic dermatitis with high safety. |
