| 摘要 |
<p>Compositions quickly disintegrating in the oral cavity which contain a filler comprising a sugar alcohol, a disintegrating agent and a lubricant. The penetration rate of ethanol into this lubricant is 3.0 x 10-3g2/sec or above. The tablet strength is 20 N or above. The compositions disintegrate in the oral cavity of normal adults within 90 seconds. Preparations disintegrating in the oral cavity which are prepared by adding drug components to these compositions disintegrating in the oral cavity. Thus, both of an appropriate strength needed in handling the preparations and quick disintegration in the oral cavity can be achieved without resort to any special production procedures or instruments.</p> |
